As of 25 May, Nigeria reported 7,839 confirmed cases of COVID-19 and 226 related deaths. Most cases (around 60%) have been registered in Lagos and Kano states, followed by the Federal Capital Territory (FCT). 35 of 37 states have reported COVID-19 cases, including conflict-affected states of Borno, Adamawa, and Yobe. Testing capacity in Nigeria is now increasing, but the health system is weak, and many areas of the countries are not easily accessible. The pandemic and COVID-19 containment measures are having a significant impact on the population’s well-being, and socioeconomic and living conditions. In this report ACAPS explains the vulnerabilities to, and impact of COVID-19 and COVID-19 containment measures in Nigeria.