Equateur province in DRC has been affected by an outbreak of the Ebola virus disease (EVD). The outbreak is believed to have begun in early April and was officially declared on 8 May. Since 3 May, 39 suspected cases have been reported, two of which have been laboratory confirmed. The full scale of the outbreak is still being determined as poor infrastructure and the remote location constrain response to the outbreak.

Intercommunal violence between Lendu and Hema communities since December has internally displaced over 300,000 people and led to a severe humanitarian crisis. In a conflict where civilians are being directly targeted, protection of the affected population is a major concern. Thousands of houses have been burned down and livelihood activities, including agriculture, have been disrupted, resulting in significant needs for shelter and food assistance.

Over 3,360 refugees from the Democratic Republic of Congo fled into Zambia between 30 August and 3 October 2017. The refugees have been fleeing inter-ethnic conflicts as well as clashes between government forces and armed militias in Haut-Katanga province. Several of them have reported extreme brutality committed by all parties against civilians. 

Fighting in and around the Kasai regions continues to cause displacement. So far, approximately 1.3 million people have fled violence in eight provinces. Between April and 22 May, over 23,500 people arrived in Angola. By mid-April 2017, at least 400 deaths had been recorded, including many civilians, but the number is likely higher. 

Since August 2016, armed clashes have occurred in Kasai-Central, Kasai Oriental, Kasai, Lomami, and Sankuru. As of mid-April 2017, at least 400 deaths have been recorded, including many civilians, but the number is likely higher. As of 27 April, at least 1.17 million people had been internally displaced due to clashes since August 2016, of whom 140,000 since mid-April.

Outbreaks of Fall Armyworm, Spodoptera frugiperda, have been reported in DRC, Zambia, Malawi, Zimbabwe, Botswana, South Africa, Namibia, Swaziland, Ghana and Kenya. Regionally, around 330,000 hectares of staple crops, especially maize, have been affected. The remaining southern African mainland countries remain at high risk. 

Since August 2016, armed clashes have taken place in Kasai and Kasai-Central. Fighting intensified in mid-December. As of mid-January, over 600 deaths have been reported. 216,000 people have been displaced by fighting in the region since August 2016. The majority of these people have reportedly fled to villages in Kasai Oriental and nearby forests. 

Since mid-July over 15,000 South Sudanese refugees have arrived in the territories of Faradge and Aru in Haut-Uele and Ituri provinces following a resurgence of violence in South Sudan. There is now a total of 27,250 registered South Sudanese refugees in the territories of Faradge and Aru in Haut-Uele and Ituri provinces. The new arrivals have received little humanitarian assistance.